Search results for "3-b]pyrazine"

showing 3 items of 3 documents

A Combined Experimental and Theoretical Study of the Ammonium Bifluoride Catalyzed Regioselective Synthesis of Quinoxalines and Pyrido[2,3-b]pyrazines

2015

International audience; Ammonium bifluoride was efficiently used (at a 0.5 mol % loading) to catalyze the cyclocondensation between 1,2-arylenediamines and 1,2-dicarbonyl compounds at room temperature in methanol-water, affording quinoxalines and pyrido[2,3-b]pyrazines in excellent yields. Importantly, 2,8-disubstituted quinoxalines and 3-substituted pyrido[2,3-b]pyrazines were regioselectively formed by reacting aryl glyoxals with 3-methyl-1,2-phenylenediamine and 2,3-diaminopyridine, respectively. Analysis of the DFT reactivity indices allowed to explain the catalytic role of ammonium bifluoride.

010405 organic chemistryChemistryOrganic ChemistryRegioselectivityAmmonium bifluoride010402 general chemistrypyrido[201 natural sciencesCatalysisammonium bifluoride0104 chemical sciencesCatalysischemistry.chemical_compoundregioselectivity3-b]pyrazinesDFT reactivity indices[CHIM]Chemical SciencesOrganic chemistryquinoxalinesDensity functional theoryReactivity (chemistry)Synthesis
researchProduct

CCDC 750746: Experimental Crystal Structure Determination

2009

Related Article: P.Koch, D.Schollmeyer, S.Laufer|2009|Acta Crystallogr.,Sect.E:Struct.Rep.Online|65|o2512|doi:10.1107/S1600536809037295

Space GroupCrystallography2-(4-Fluorophenyl)-3-(pyridin-4-yl)pyrido[23-b]pyrazineCrystal SystemCrystal StructureCell ParametersExperimental 3D Coordinates
researchProduct

CCDC 750773: Experimental Crystal Structure Determination

2009

Related Article: P.Koch, D.Schollmeyer, S.Laufer|2009|Acta Crystallogr.,Sect.E:Struct.Rep.Online|65|o2546|doi:10.1107/S1600536809037970

Space GroupCrystallographyCrystal SystemCrystal StructureCell ParametersExperimental 3D Coordinates3-(4-Fluorophenyl)-2-(pyridin-4-yl)pyrido[23-b]pyrazine
researchProduct